rabbit antislc3a2 Search Results


rabbit anti slc3a2  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc rabbit anti slc3a2
Rabbit Anti Slc3a2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti slc3a2/product/Cell Signaling Technology Inc
Average 95 stars, based on 1 article reviews
rabbit anti slc3a2 - by Bioz Stars, 2026-03
95/100 stars
  Buy from Supplier
13180s  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc 13180s
13180s, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/13180s/product/Cell Signaling Technology Inc
Average 94 stars, based on 1 article reviews
13180s - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
rabbit anti slc3a2  (Boster Bio)
92
Boster Bio rabbit anti slc3a2
Rabbit Anti Slc3a2, supplied by Boster Bio, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti slc3a2/product/Boster Bio
Average 92 stars, based on 1 article reviews
rabbit anti slc3a2 - by Bioz Stars, 2026-03
92/100 stars
  Buy from Supplier
rabbit polyclonal anti slc3a2  (Proteintech)
96
Proteintech rabbit polyclonal anti slc3a2
Rabbit Polyclonal Anti Slc3a2, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anti slc3a2/product/Proteintech
Average 96 stars, based on 1 article reviews
rabbit polyclonal anti slc3a2 - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier
anti slc3a2  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc anti slc3a2
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Anti Slc3a2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti slc3a2/product/Cell Signaling Technology Inc
Average 95 stars, based on 1 article reviews
anti slc3a2 - by Bioz Stars, 2026-03
95/100 stars
  Buy from Supplier
rabbit anti slc3a2  (Biosynth Carbosynth)
88
Biosynth Carbosynth rabbit anti slc3a2
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Rabbit Anti Slc3a2, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti slc3a2/product/Biosynth Carbosynth
Average 88 stars, based on 1 article reviews
rabbit anti slc3a2 - by Bioz Stars, 2026-03
88/100 stars
  Buy from Supplier
rabbit polyclonal anti slc3a2 proteintech  (Proteintech)
96
Proteintech rabbit polyclonal anti slc3a2 proteintech
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Rabbit Polyclonal Anti Slc3a2 Proteintech, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anti slc3a2 proteintech/product/Proteintech
Average 96 stars, based on 1 article reviews
rabbit polyclonal anti slc3a2 proteintech - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier
anti cd98 antibody  (Boster Bio)
93
Boster Bio anti cd98 antibody
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Anti Cd98 Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti cd98 antibody/product/Boster Bio
Average 93 stars, based on 1 article reviews
anti cd98 antibody - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
rabbit-anti-slc3a2  (Cell Signaling Technology Inc)
90
Cell Signaling Technology Inc rabbit-anti-slc3a2
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Rabbit Anti Slc3a2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit-anti-slc3a2/product/Cell Signaling Technology Inc
Average 90 stars, based on 1 article reviews
rabbit-anti-slc3a2 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
anti-slc3a2  (Santa Cruz Biotechnology)
90
Santa Cruz Biotechnology anti-slc3a2
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Anti Slc3a2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-slc3a2/product/Santa Cruz Biotechnology
Average 90 stars, based on 1 article reviews
anti-slc3a2 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
anti mkl 1  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc anti mkl 1
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Anti Mkl 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti mkl 1/product/Cell Signaling Technology Inc
Average 94 stars, based on 1 article reviews
anti mkl 1 - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
anti slc3a2 antibody  (Proteintech)
96
Proteintech anti slc3a2 antibody
RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, <t>SLC3A2,</t> Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.
Anti Slc3a2 Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti slc3a2 antibody/product/Proteintech
Average 96 stars, based on 1 article reviews
anti slc3a2 antibody - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier

Image Search Results


RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, SLC3A2, Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.

Journal: EMBO Reports

Article Title: APEX2‐mediated RAB proximity labeling identifies a role for RAB21 in clathrin‐independent cargo sorting

doi: 10.15252/embr.201847192

Figure Lengend Snippet: RAB21 is required for endosomal sorting of direct clathrin‐independent cargos. RAB21 associates with WASH/retromer subcomplexes at endosomes. RAB21 could either (i) recruit WASH/retromer or (ii) be recruited by WASH/retromer or (iii) be part of a positive feedback loop that would allow WASH/retromer and RAB21 recruitment at endosomes. Endosomal RAB21 would be required for WASH‐mediated F‐actin polymerization. Although the data do not directly demonstrate a direct link between F‐actin generation and cargo sorting, we propose that RAB21‐dependent F‐actin generation would be required for sorting of a CIE cargo subclass (MCT1, SLC3A2, Basigin, and CD44), while it would not be required for other cargos (CI‐MPR or Glut1). In RAB21 knockout cells, decreased WASH/retromer endosomal localization is observed, which results in reduced endosomal F‐actin and direct CIE cargo misrouting. This ultimately leads to the lysosomal degradation of these misrouted cargos (demonstrated for SLC3A2). Dotted line between VARP and RAB21 indicates that their coregulation with the retromer is speculative.

Article Snippet: Antibodies used for immunoblotting were anti‐GFP (1:500, Roche #11814460001), anti‐RAB21 (1:1,000, Sigma #R4405 or 1:1,000, Invitrogen #PA5‐34404), anti‐RAB4 (1:1,000, Cell Signaling #2167), anti‐RAB5 (1:1,000, Cell Signaling #3547), anti‐RAB7 (1:1,000, Cell Signaling #9367), anti‐GAPDH‐HRP (1:1,000, Cell Signaling #8884), anti‐Myc (1:1,000, Cell Signaling #2278), anti‐HA (1:1,000, Cell Signaling #3724), anti‐SLC3A2 (1:800, Cell Signaling #13180), anti‐Strumpellin (1:500, Santa Cruz #377146), anti‐VPS35 (1:500, Santa Cruz #374372), anti‐VPS26 (1:500, Santa Cruz #390304), anti‐VPS29 (1:500, Santa Cruz #398874), anti‐FAM21 and anti‐WASH (1:10,000, gift from D. Billadeau), anti‐CAPZα (1:500, Santa Cruz #374302), anti‐APPL1 (1:1,000, Cell Signaling #3858), anti‐VARP (1:500, Bethyl Laboratories #A302‐997A), anti‐tubulin (1:2,500, Sigma #T9026), streptavidin‐HRP (1:1,000, Thermo Fisher #N100), and anti‐rabbit and mouse HRP (1:10,000, Jackson Laboratories #115‐035‐144 and #115‐035‐146, respectively).

Techniques: Knock-Out